Alexander VI (1431 – 1503)
- Pope Alexander VI (1431 – 1503), born Roderic Llançol i de Borja 1492-1503
Pius III (1439 – 1503)
- Pope Pius III (1439 – 1503), born Francesco Todeschini Piccolomini 1503
Julius II (1443 – 1513)
- Pope Julius II (1443 – 1513), born Giuliano della Rovere 1503-1513 See della Rovere
Leo X (1475 – 1521)
- Pope Leo X (1475 – 1521), born Giovanni di Lorenzo de' Medici 1513-1521 See Tuscany
Adrian VI (1459 – 1523)
- Pope Adrian VI (1459 – 1523), born Adriaan Florensz Boeyens 1522-1523
Clement VII (1478 – 1534)
- Pope Clement VII (1478 – 1534), born Giulio di Giuliano de' Medici 1523-1534 See Tuscany
Paul III (1468 – 1549)
- Pope Paul III (1468 – 1549), born Alessandro Farnese 1534-1549 See Parma
Julius III (1487 – 1555)
- Pope Julius III (1487 – 1555), born Giovanni Maria Ciocchi del Monte 1550-1555
Marcellus II (1501 – 1555)
- Pope Marcellus II (1501 – 1555), born Marcello Cervini degli Spannochi 1555
Paul IV (1476 – 1559)
- Pope Paul IV, C.R. (1476 – 1559), born Gian Pietro Carafa 1555-1559
Pius IV (1499 – 1565)
- Pope Pius IV (1499 – 1565), born Giovanni Angelo de' Medici 1559-1566 See Tuscany
Pius V (1504 – 1572)
- Pope Pius V (1504 – 1572), born Antonio Ghislieri 1566-1572
Gregory XIII (1502 – 1585)
- Pope Gregory XIII (1502 – 1585), born Ugo Boncompagni 1572-1585 See Boncompagni
Sixtus V (1521 – 1590)
- Pope Sixtus V (1521 – 1590), born Felice Peretti di Montalto 1585-1590
Urban VII (1521 – 1590)
- Pope Urban VII (1521 – 1590), born Giovanni Battista Castagna 1590
Gregory XIV (1535 – 1591)
- Pope Gregory XIV (1535 – 1591), born Niccolò Sfondrati 1590-1591
Innocent IX (1519 – 1591)
- Pope Innocent IX (1519 – 1591), born Giovanni Antonio Facchinetti 1591
Clement VIII (1536 – 1605)
- Pope Clement VIII (1536 – 1605), born Ippolito Aldobrandini 1592-1605 See Aldobrandini