Thomas of Woodstock (1355 –1397) 1st Duke of Gloucester
- Thomas of Woodstock (1355 –1397) 1st Duke of Gloucester, 1st Earl of Buckingham, 1st Earl of Essex. Married Eleanor de Bohun (c. 1366–1399) daughter of Humphrey de Bohun, 7th Earl of Hereford. See House of Planagenet
Children of Thomas of Woodstock and Eleanor de Bohun:
Humphrey (c. 1381 – 1399) 2nd Earl of Buckingham
- Humphrey (c. 1381 – 1399) 2nd Earl of Buckingham
Anne of Gloucester (1383 – 1438)
- Anne of Gloucester (1383 – 1438) Married firstly Thomas Stafford, 3rd Earl of Stafford (1368 - 1392), secondly Edmund Stafford (1378 – 1403) 5th Earl of Stafford and thirdly William Bourchier (d. 1420) 1st Count of Eu.
Children of Anne of Gloucester and Edmund Stafford:
Humphrey Stafford (1402 –1460) 1st Duke of Buckingham
- Humphrey Stafford (1402 –1460) 1st Duke of Buckingham, 6th Earl of Stafford. Married Anne Neville (d.1480) daughter of Ralph Neville, 1st Earl of Westmorland.
Anne Stafford (d. 1432)
- Anne Stafford (d. 1432) Married firstly Edmund Mortimer (1391 – 1425) 5th Earl of March and Ulster. Heir presumptive to Richard II, King of England and secondly John Holland (1395 – 1447) 2nd Duke of Exeter, 2nd Earl of Huntingdon.
Children of Anne of Gloucester and William Bourchier:
Sons of 1st Duke of Buckingham:
Humphrey Stafford (c. 1425 – 1458) Earl of Stafford
- Humphrey Stafford (c. 1425 – 1458) Earl of Stafford. Married Margaret Beaufort (c. 1437 – 1474) daughter of Edmund Beaufort, 2nd Duke of Somerset
Sir Henry Stafford (c. 1425 – 1471)
- Sir Henry Stafford (c. 1425 – 1471). Married as her third husband Lady Margaret Beaufort (1441 – 1509) daughter of John Beaufort, 1st Duke of Somerset and mother of King Henry VII.
John Stafford (1427 – 1473) 1st Earl of Wiltshire
- John Stafford (1427 – 1473) 1st Earl of Wiltshire. Married Constance Green (1427 – 1474) daughter of Sir Henry Green of Drayton
Son of Humphrey Stafford, Earl of Stafford:
Henry Stafford (1455 – 1483) 2nd Duke of Buckingham
- Henry Stafford (1455 – 1483) 2nd Duke of Buckingham. Married Catherine Woodville (c. 1458 –1497) daughter of Sir Richard Woodville, 1st Earl Rivers and Jacquetta of Luxembourg.
Children of 2nd Duke of Buckingham:
Edward Stafford (1478 – 1521) 3rd Duke of Buckingham
- Edward Stafford (1478 – 1521) 3rd Duke of Buckingham. Married Eleanor Percy (c. 1474 – 1530) daughter of Henry Percy, 4th Earl of Northumberland.
Elizabeth Stafford (c. 1479 – 1532)
- Elizabeth Stafford (c. 1479 – 1532) Married Robert Radcliffe (c. 1483 – 1542) 10th Baron Fitzwalter, 1st Earl of Sussex.
Henry Stafford (c. 1479 – 1523) 1st Earl of Wiltshire
- Henry Stafford (c. 1479 – 1523) 1st Earl of Wiltshire. Married Cecily Bonville (1460 – 1529) 7th Baroness Harington, 2nd Baroness Bonville daughter of William Bonville, 6th Baron Harington.
Anne Stafford (c. 1483 – 1544)
- Anne Stafford (c. 1483 – 1544) Married George Hastings (1488 – 1544) 1st Earl of Huntingdon.
Children of 3rd Duke of Buckingham:
Lady Mary Stafford (1495 – 1545)
- Lady Mary Stafford (1495 – 1545) Married George Nevill (c.1469 – 1535) 5th Baron Abergavenny
Lady Elizabeth Stafford (c. 1497 –1558)
- Lady Elizabeth Stafford (c. 1497 –1558) Married Thomas Howard (1473 – 1554) 3rd Duke of Norfolk
Lady Katherine Stafford (c. 1499 – 1555)
- Lady Katherine Stafford (c. 1499 – 1555) Married Ralph Neville (1498 – 1549) 4th Earl of Westmorland
Henry Stafford (1501 – 1563) 1st Baron Stafford
- Henry Stafford (1501 – 1563) 1st Baron Stafford. Married Ursula Pole (c. 1504 – 1570) daughter of Sir Richard Pole and Margaret Pole, 8th Countess of Salisbury daughter of George Plantagenet, 1st Duke of Clarence.
Son of John Stafford, 1st Earl of Wiltshire:
Edward Stafford (1470 – 1499) 2nd Earl of Wiltshire
- Edward Stafford (1470 – 1499) 2nd Earl of Wiltshire. Married Margaret Grey (1481 – 1504) daughter of Edward Grey, 1st Viscount Lisle
Barons Stafford in the peerage of England, fourth creation (1547-1640)
- Henry Stafford, 1st Baron Stafford (1501–1563) In 1558, his title was recognized as carrying precedence from 1299. See above
- Henry Stafford, 2nd Baron Stafford (d. 1566)
- Edward Stafford, 3rd Baron Stafford (1536–1603)
- Edward Stafford, 4th Baron Stafford (1572–1625)
- Henry Stafford, 5th Baron Stafford (1621–1637)
- Roger Stafford, 6th Baron Stafford (c. 1573–1640) Charles I denied his claim to the title on grounds of Stafford's poverty and it was surrendered in 1637.